Also known as Nutrabol, MK677 is a drug which falls somewhere between two separate groups of drugs, growth hormone secretagogues (GSH) and selective androgen receptor modulators (SARMs).
Manufactured by Reverse Pharmacology, MK677 was originally developed to treat medical conditions which involve muscle wasting as well as osteoporosis and obesity. With particular emphasis on treating elderly patients with fractured hips, there’s been a plethora of safety studies on this drug.
MK677 works by sending off signals to the pituitary gland in the brain, telling it to release growth hormone. This is a very similar action to peptides such as GHRP-6 so although it is often grouped with SARMs, it doesn’t strictly act in the same way.
The drug also works to boost IGF-1 by as much as 89%, which helps to provide a raft of other benefits too such as improved healing.
The bodybuilding community uses MK677 stacks for cutting and bulking to great effect, and it’s a popular drug because of the relatively low cost.
MK677 is a very powerful drug which can be used for both cutting and bulking to great effect.
A solo MK677 cycle is sufficient to deliver impressive fat loss combined with a significant increase in lean muscle tissue.
However, the drug has very few, if any, interactions so can be run alongside other compounds including HCG, SARMs and anabolic steroids. Therefore if you want to create a MK677 super stack, you can expect some of the best results possible.
How it is administered
MK677 is very popular with those who don’t like injections because it has an oral bioavailability. This means it can be taken by mouth without causing any toxicity to the liver, or being metabolized too quickly by the body.
There are liquid and tablets available, both of which are stored at room temperature making it a convenient choice for those who travel.
The recommended dosage of MK677 is 5-25mg daily, taken in a 10-week cycle. It may be necessary to adjust the dose to continue to get optimal results and in some cases up to 50mg has been taken, but that’s not generally necessary or advisable.
The liquid form should be squirted straight into the mouth and chased down with water or juice. It shouldn’t be mixed before drinking.
Half life info
The half life of MK677 is 24 hours so you’ll only need to take it once a day. The most common route of administration is the liquid form, taken on an empty stomach first thing in the morning, every day.
Those who take MK677 suggest that it’s almost impossible to gain fat while taking the drug, so strong is its fat loss effect.
You can stack it with other SARMs such as cardarine or andarine for a fat-burning cycle which is incredibly potent, or take it alone and you’ll still achieve a shredded appearance. The other benefit is that MK677 packs on lean tissue so even if you’re on a calorie restricted diet, you will still hang on to your muscle.
Because of the interaction with IGF-1, MK677 can provide phenomenal results on a bulking cycle.
IGF-1 is the only hormone that can create new muscle cells, so MK677 will help to pack on serious mass very quickly.
On an MK677 bulking cycle you can expect to gain several pounds rapidly and continue to gain for the rest of the cycle. It’s a compound which delivers fast results without compromising on the quality.
A bulking cycle often means accumulating an increase in body fat temporarily, but that isn’t the case with MK677. You won’t be piling on unwanted fat that you’ll need to later shed making it perfect for bulking either on its own or in a stack.
MK677 works by promoting the release of growth hormone in the body. It manages this by stimulating the pituitary gland directly.
An MK677 cycle will help to promote the amount of lean tissue in the body but it’s believed that it doesn’t affect the fat cells directly. Instead, the increase in lean tissue comes from the calorific depositions into the muscles, avoiding fat storage completely. It also has the effect of decreasing the appetite plus increasing the basal metabolic rate.
Additional benefits include an improvement in bone density so MK677 has the potential to aid with recovery too.
Unlike anabolic steroids, there’s a whole plethora of beneficial side effects including a better complexion, good sleep, heightened energy levels, rise in nitrogen retention, improved immune system response and a general sense of well-being.
For bodybuilders, the benefit to taking MK677 is greater lean mass and lower fat stores.
It also naturally pushes up IGF-1 which increases fat loss and muscle gains, tightens loose skin and heals old injuries, ligaments, tendons and bones. IGF-1 is expensive and difficult to administer, by taking MK677 all the benefits of IGF-1 can be gained, without the same problems or the high cost.
Potential side effects
Although MK677 side effects aren’t as bad as those experienced with an anabolic steroid, it’s not without problems.
Any drug which raises growth hormone levels typically causes lethargy, numb hands and an increase in appetite and for some users, MK677 is no exception.
When the compound is first started, prolactin may increase so individuals who are sensitive to this effect may need to run HCG alongside it at the start.
Only a small percentage of individuals will be sensitive to prolactin, typically around 1%. As a general guide, if you suffer gyno effects when you take trenbolone, you’d be wise to run HCG with MK677.
MK677 is a very safe drug to take, with few contraindications to use.
However, because of its interaction with IGF-1, and the potential to increase cell division, you should take advice from a physician before taking it if you have a history of tumors, growths or cancer.
It’s also not been demonstrated as safe to take for pregnant or breastfeeding women.
Is it safe for women to use?
There’s no androgenic effects from the use of MK677 which means that it won’t virilize in women.
This means that MK677 is safe for women to take. Similar doses to men can be used, but due to the large amounts of growth hormone produced, starting with 10mg is recommended.
Will PCT be required?
Although MK677 is often grouped with SARMs, it doesn’t affect the body in the same way, bearing a closer resemblance to some peptides instead.
If you want to buy MK677 online, you’ll find a great variety of sources because it’s a drug that’s rapidly rising in popularity.
IGF-1 can be expensive, but with a 90-day supply of tablets available for around $60 buying MK677 is a much cheaper option.
Legality of purchase and its usage in the US
SARMS, including MK677, are capable of producing results which can rival anabolic steroids but they aren’t subject to the same stiff federal penalties.
Thanks to a loophole in US law, MK677 for sale can be found online for research purposes. Although it doesn’t yet have a license for human consumption it can be freely bought for research, which allows it to be purchased without a hefty fine, or even a jail sentence.