S4 (Andarine)

S4 andarine is a type of drug known as a selective androgen receptor modulator (SARMS), a group which mimic the effects of anabolic steroids without causing the same harsh effects.

When it was first created, this SARM supplement was intended to be used within the medical sphere, and offered as a treatment for conditions such as benign prostate hypertrophy, osteoporosis and muscle wasting in diseases such as cancer and HIV.

It works by binding to the androgen receptor but unlike steroids, it is specific to bone and muscle tissue so doesn’t attract the same degree of side effects. This action increases protein synthesis, helping to increase lean muscle mass without bloating.

Stacking info

Andarine can be used on its own, particularly to increase strength and for cutting, but it’s at its most effective when used in a stack. This can either be other SARMS or it can be used to enhance the actions of anabolic steroids, while simultaneously minimizing side effects.

How it is administered

When taking S4, liquid is the most common form of the drug and it can be purchased in differing volumes and concentrations.

Although it can be taken for quite a prolonged cycle, the typical recommendation is that it’s administered for only five days out of every seven. Some users opt for a 5 on, 2 off regime while others prefer to have a single day off in the middle of the week and another one at the end. This latter regime ensures that the SARM cycle is kept fairly constant without fluctuating blood levels.

Dosage info

An effective dose to get the very best SARMS results from S4 starts at around 50mg, for cutting, recomping and strength. This is typically taken in a divided dose because of the short half life (see below).

Some users may opt to increase the S4 dosage to 75mg for maximum benefit.

Half life info

The half life of andarine is just between 4-6 hours, making it a short-acting drug. For this reason, many users opt to split the dose.

Use in sports

S4 has been shown to produce desirable effects within bodybuilding and for this reason it’s sought after within the community. However, its ability to optimize lean muscle mass and enhancing strength has also meant the andarine has been used in a number of other sports too such as cycling, athletics and baseball.


Studies have shown that S4 results outperform anabolic steroids when it comes to fat loss and getting ripped.

Andarine S4 is naturally inclined to create a shredded and ripped appearance, making it a popular choice prior to competitions. It can either be added to an anabolic steroid to boost a cutting cycle or a SARMS stack can be created, adding cardarine for a potent fat loss cycle.


Although a very popular type of SARMS, S4 is not the best choice for users who are looking to bulk up. With sufficient exercise and extra calories, andarine can pack on lean muscle gains but there won’t be the rapid growth typically seen during a bulking cycle when it’s used solo.

However, when S4 is added to a bulking stack, it can be extremely useful, enhancing the actions of other bulking drugs while also reducing puffiness and increasing lean mass.

Strengthening and recomping

Andarine is excellent at ramping up strength, giving gains which are not just fast and clean, but also very easy to maintain. If strength is the main goal, a dosage of around 50mg should be taken, potentially increasing to 75mg. S4 is one of the best SARMS for ramping up strength, with results starting to become evident in just over a week.

S4 is also perfect for recomping when stacked with another SARM which has a slightly more anabolic effect, such as Ostarine. For this purpose the drug should be taken at 50-75mg for a period of 4-8 weeks.

For maximum recomping, Andarine should be stacked with Ostarine and Cardarine for a triple stack which delivers the best results without noticeable side effects. In addition, a diet which has a minimum of 30% of calories coming from lean protein will be of significant benefit too.

Positive effects

There’s a whole host of performance benefits which can be gained by using Andarine.

It has an excellent ability to increase skeletal muscle strength as well as lean body mass while simultaneously getting rid of body fat. Unlike some other types of supplement, this fat loss doesn’t cause catabolism. Andarine S4 also dries out muscle, providing a lean, hard appearance which is one of the reasons why it’s so popular as a pre-competition drug.

Some studies suggest that S4 can be used to reduce gynecomastia because of its very slightly androgenic effect.

Outside SARMS bodybuilding use, andarine also has been shown to be effective in the treatment of muscle wasting disease as well as benign prostate hypertrophy.

Potential side effects

SARMS side effects do occur but S4 is one of the less risky compounds because it was originally developed for medicinal use. This means that side effects are very minimal compared to some of the other SARMS, and certainly virtually non-existent compared to anabolic steroids.

There are no androgenic, estrogenic or hepatotoxic side effects of S4, nor has any negative impact on the cardiovascular system been demonstrated.

Some users have reported a yellowing of their eyes or a deterioration in their night vision but this isn’t a universal effect. If this occurs, cessation of the drug will resolve the problem.


There are no documented contraindications for S4 SARM use.

Is it safe for women to use?

This SARM supplement does not have any noticeable androgenic effect so there is no chance that virilization will occur in women.

Andarine can be taken safely by women without any of the risks of developing excess body hair, enlargement of the clitoris or a deepening of the voice such as with anabolic steroids.

Will PCT be required?

The S4 SARMS supplement does have the effect of suppressing the natural production of testosterone but to a much lesser degree than with anabolic steroids. Therefore, there’s no clear cut answer as to whether PCT is required but the general consensus is that it’s a good idea.

If the S4 SARM is used in a stack with an anabolic steroid, PCT will be essential.

Typical cost

S4 Andarine is one of the SARMS available for sale online but it’s important to be able to trust the integrity of the seller. If you can find a reputable source, the internet is the best place to buy SARMS such as S4 Andarine.

For a bottle of 30 ml Andarine, at a concentration of 50mg per ml, expect to pay in the region of $150.

Legality of purchase and its usage in the US

It is possible to buy SARMS online without breaking the law, unlike anabolic steroids, but currently it still remains somewhat a grey area.

The FDA haven’t included SARMS in the same legislation which prohibited the sale, distribution or purchase of anabolic steroids, but it’s expected that this may change in the not too distant future.

In addition, although it is relatively simple to buy SARMS online, there are some suggestions that it should technically be classed as a medical compound, not a nutritional supplement, because this is what it was originally developed for. If this was to be the case, it would fall under the remit of the FDA.

For this reason, SARMS S4 for sale will often contain a disclaimer which will typically state that the drug is being sold for the purposes of “chemical research”. This means that the S4 “research chemical” should not be consumed or taken internally.

SARMS are also available to freely buy in the UK and throughout Europe.

Source: Sarms1.com

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